Maybe one of the more "obscure" operations when dealing with replica lag, or, in general, when one needs to control writes to the database, is the Rate limit. It's also lately one of the most popular conversations around the community.
But what is it? In plain words: holding up queries for a while, giving air to the replicas to breath and catch up. Something similar to the Galera's Flow Control mechanism, although flow control, when it kicks in, stops all the writes while the nodes catch up. With a throttle no write is stopped, just delayed.